
Drug Docking Studies / Structure based Drug Design
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Target Validation of proteins involved in various biochemical pathways.
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Virtual Screening of ligands in chemical databases against Protein Targets.
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Docking of Small molecule ligands and peptides against protein targets of known structure and computing their binding free energy.
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Homology modeling of protein targets whose structure is not yet determined.
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Docking of Small molecule ligands and peptides against modeled protein structures and computing their binding free energy.

SAR / QSAR Studies (Pharmacophore mapping)
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LIGAND BASED RATIONAL DRUG DESIGN - Structure-activity relationship and Quantitative Structure-activity Relationship approaches in Computer-Aided Drug Design.

Bio-Molecular Simulations
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Molecular Dynamic Simulations of proteins in different conditions.
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Calculating the free energy change of enzyme mutants.
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Accurate calculation of binding free energy of protein-drug complexes.
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Calculating other thermodynamic parameters like enthalpy change and conformational entropy change from MD trajectories.

Protein Engineering
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Design of Stable Proteins and Enzymes for industrial applications.
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Predicting the Thermo-stability of enzyme mutants.
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Predicting the stability of enzymes/proteins at altered pH conditions, ionic strengths and in presence of organic solvents.
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Site-directed Mutagenesis - Design of oligonucleotide primers for to introduce specific mutations in proteins/enzymes.
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Design of site-specific mutations and smart libraries in protein engineering.
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Disulfide engineering in proteins to increase stability.
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Design of enzyme mutants to overcome product inhibition.

HPLC
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Analysis of pharmaceutical compounds and natural phytochemicals, peptides and proteins.
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Purification of peptides/phytochemicals using HPLC.

Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry based Analysis
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Structure determination of small molecule ligands and peptides using NMR, IR and Mass Spectrometry.
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Interpretation of Mass Spectrometric Data of ligands, peptides and proteins.
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Interpretation of NMR Data of ligands, peptides and proteins.
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Study of Protein dynamics using NMR.
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Study of Protein-drug interactions and Protein-protein interactions using NMR and HDX based Mass Spectrometry.

Omics Data Analysis
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Genomics - Next Generation Sequencing (NGS) Data Analysis.
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Transcriptomics - MicroArray Data Analysis and SAGE Data Analysis.
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Proteomics - Image Processing of 2D gels, Protein Sequencing using mass spectrometry, Protein Identification and their Post Translational Modifications using Mass spectrometry, Interpretation of Proteomics Data.
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Quantitative Proteomics and Targeted Proteomics.
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Metabalomics - Identification of metabolites from clinical samples.

Fermentation Technology
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Statistical optimization of various parameters in fermentation.
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Expression of Recombinant Proteins in fermenters.
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Design and optimization of Solid-state fermenters.

Training/Internships/Projects
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BIOINFORMATICS - Drug Design, Bioinformatics approaches in CRISPR Technology, Protein Engineering, Computational Genomics and Proteomics.
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HPLC Training - HPLC based purification and analysis of pharmaceuticals, natural phytochemicals and peptides.
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Training in NMR and Mass Spectrometry Data Analysis.
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Training in Fermentation Technology.
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Training in CRISPR Technology.

Workshops and Popular Talks
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Regular workshops on CRISPR Technology, Drug Design and Development, UNIX for biologists, Protein Engineering, Bio-molecular simulations in Drug Discovery, Structural Biology.

Courses
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Certificate course on CRISPR/CAS9 Technology.
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Certificate course on Drug Design.

Coaching Classes for Competitive Entrance Exams
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GATE (Biotechnology/Life Sciences)
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GPAT
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CSIR/ICMR JRF
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NEET and other Medical Entrance Exams